Extraction, essential oils and active ingredients of medicinal plants

Some of the techniques presented in Histogenotech

Plants are rich and diverse sources of food colors, antioxidants, flavorings, fragrances and extracts and can meet the needs of the pharmaceutical and chemical industries. Histogenotech Research Center has started this section with the aim of commercializing research findings and producing various types of extracts and effective herbal substances.

Due to the importance of natural products, the consumption of various extracts and essential oils obtained from medicinal plants is very crucial today. The global organization’s emphasis on the gradual replacement of natural active ingredients with chemical active ingredients in the food, health, cosmetics, and especially pharmaceutical industries has led various countries to invest in and plan for the production of industrial herbal products.

Plant Studies Services

Maceration method

Infusion method

Digestion

Decoction method

Percolation method

Soxhlet extraction

Microwave extraction

Extraction by ultrasonic method

Maceration method

Infusion method

Digestion

Decoction method

Percolation method

Soxhlet extraction

Microwave extraction

Extraction by ultrasonic method

PRODUCTION OF METAL NANOPARTICLES

Metals such as silver, gold, zinc, etc. are used to make nanoparticles. These particles have received much attention in nanotechnology due to their anti-inflammatory, antimicrobial effects. These particles are conductive in the human body due to their unique electrical and magnetic properties. Histogenotech nanotechnology unit is ready to provide services to researchers in the field of metal nanoparticles by using expert staffs and also using modern methods of synthesis and study of these particles.

PRODUCTION OF POLYMER NANOPARTICLES

Polymer nanoparticles (hydrogels) are three-dimensional polymer networks used to encapsulate and transport different factors like drugs, growth factors, and large molecules.To date, the Histogenotech Knowledge Base institute has developed more than 20 different projects in the field of metal nanoparticle synthesis and is still ready to provide polymer nanoparticle synthesis services (chitosan and liposomal).

PRODUCTION OF NANO-EMULSIONS

Nano-emulsions are nano-sized structures that result from the integration of two non-integral phases such as water (W) and oil (O). The use of nano-emulsions is increasing in different industries such as pharmaceutical, cosmetic and food due to their greater stability and physical and chemical properties. Using the latest published methods and relying on the potential of its specialists, the Histogenotech nanotechnology department provides nano-emulsion synthesis services to researchers.

Production of plant essential oils

Essential oils (essential oils) are one of the most important active ingredients in medicinal plants. These substances are present in many parts of medicinal plants and contain different compounds such as hydrocarbons, alcohols, ketones, aldehydes, ethers, esters, which have many biological effects and activities. Histogenotech knowledge-based institute with equipped semi-industrial and industrial lines, is ready to provide services in the field of extraction different substances from medicinal plants.

Production of herbal medicine oils

Herbal medicine oils are fatty acids that are extracted from different parts of the plant, such as seeds. Like animal fats, they are rich in triglyceride fatty acids and, unlike essential oils, have a sour smell and taste when left in the environment. These compounds are very important in many different industries, especially food and cosmetics. Histogenotech is ready to provide services in the field of Herbal medicine oil extraction by distillation and cold pressing, on a semi-industrial and industrial scale.

Production of metal nanoparticles

Production of polymer nanoparticles

Production of nano-emulsions

Production of plant essential oils

Production of herbal medicine oils

You may find the answer to your question

Frequently Asked Questions by Customers

What is the best way to extract a plant extract for biological study?

In biological studies, it is often better to use methods that do not use heat to investigate the effects of active substances on biological processes. Because the active ingredients are sensitive to temperatures above 70-60 degrees Celsius. The proposed method for extraction in biological studies is the maceration method.

How much essential oil can be extracted from one kilo of fresh plant?

Plants are classified based on essential oils. Some, such as sage, are low in essential oils and some plants, such as rosemary, are high in essential oils. In addition, environmental conditions and geographical area of cultivation also affect the amount of volatile fatty acids (essential oils) of the plant. In general, there is no rule on how much essential oil is obtained from one kilo of plant and there is a need for trial and examination. Of course, the Histogenotech has performed this examination for many plants, which makes it easier for clients to have a pure essential oils.

Is there a difference between vegetable essential oils and vegetable oils?

Essential oils (essential oils) are one of the most important active ingredients in medicinal plants. These substances are present in many parts of various medicinal plants. Essential oils evaporate if exposed to normal temperatures. Hence they are called volatile oils and the specific odor of some plants is related to this group of compounds. Essential oils differ from fixed oils in some chemical and physical properties, the most important of which are: 1. Essential oils can be distilled and therefore can be easily extracted through distillation methods. 2. The chemical structure of essential oils is not made from glycerin esters and fatty acids, unlike fixed oils. 3. Unlike essential oils, essential oils do not spoil or turn sour. Instead, they will form oxidized and resin in the presence of air and light.

How should we choose solvent to evaluate the performance of herbal active ingredients?

Different solvents (water, ethanol, methanol, water-alcohol combination, hexane, etc.) can be used for extraction. But the choice of solvent depends on the properties of the active ingredients. For example, polarity, solubility and many other factors should be considered for solvent.

After extracting from ginger plant, how can the concentration and dose of the extract be obtained?

There are a variety of methods for concentrating plant extracts. But the easiest way is to pour a certain amount of extract (for example, 5 ml) in a pre-weighed plate. Place the plate in a high temperature oven and weigh it again after the liquid is completely dry. With this method, it is easy to find out the concentration and amount of extract in the liquid.

Can the active ingredient of menthol be isolated from the plant extract of mint?

Yes, the extraction of certain plant active ingredients can be done from plant extracts and requires special equipment such as chromatography. For example, the HPLC method, which is a chromatographic method, can be used to both identify and determine the presence of an active substance and to extract that active substance.

How much plant is needed to get 1 kg of total extract?

Like essential oils, the amount of active ingredients in plants varies. In general, it can be said that three different factors affect the amount of extract. 1. Differences in cultivated geographic conditions like light conditions and other environmental conditions. 2. Differences in solvent used for extraction. 3. The plant organ that is selected for extraction (for example, the leaves of plants are a richer area than the seed for extraction).

What should be the quality of the plant extract that we prepared for rat gavage?

The extract should be clear, free of foreign particles, without turbidity and sediment. The color of the extract should be appropriate for the plant and the ingredients in it. The smell of the extract should be similar to the smell of the plant. However, some extracts are less aromatic due to the use of glycolic solvents, especially hydro-glycolic extracts. Although some extracts contain antibacterial agents, laboratory bacteriological tests are sometimes needed to evaluate the contamination of extract.